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Hyperlipoproteinemia - Symptoms and Treatment

Hyperlipoproteinemia refers to a group of acquired and inherited disorders whose common denominator is excessive levels of lipids (fats) in the blood, caused by a metabolic disorder. It is also referred to as hyperlipidemia. The condition is a major cause of coronary heart disease (CHD). Levels of lipoproteins (and therefore lipids, particularly LDL cholesterol) increase slightly as people age. Levels are normally slightly higher in men than in women, but levels increase in women after menopause. The increase in levels of lipoproteins that occurs with age can result in hyperlipoproteinemia and increase the risk of atherosclerosis. (A high level of HDL the good cholesterol is beneficial and is not considered a disorder.) Factors that increase the risk of hyperlipoproteinemia include having close relatives who have had hyperlipoproteinemia (having a family history of the disorder), being overweight, consuming a diet high in saturated fats and cholesterol, being physically inactive, and consuming a moderate to excessive amount of alcohol. Some disorders, including some hereditary disorders cause lipid levels to increase. Diabetes that is poorly controlled or kidney failure can cause total cholesterol levels or triglyceride levels to increase. Obstructive liver disease and an underactive thyroid gland (hypothyroidism) can cause the total cholesterol level to increase. Use of drugs such as estrogens premarin (taken by mouth), oral contraceptives, corticosteroids, and thiazide diuretics (to some extent) can cause triglyceride levels to increase.



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