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Parkinson's Disease - Symptoms and Treatment
Parkinson's Disease is a chronic, progressive neurodegenerative movement disorder. Tremors, rigidity, slow movement (bradykinesia), poor balance, and difficulty walking (called parkinsonian gait) are characteristic primary symptoms of Parkinson's disease.It is a progressive neurological disorder that results from degeneration of neurons in a region of the brain that controls movement.
Causes of Parkinson's Disease
Low levels of dopamine, a brain chemical (neurotransmitter) involved in controlling movement, cause symptoms of Parkinson's disease. The shortage of this brain chemical occurs when nerve cells in a part of the brain (substantia nigra) that produces dopamine fail and deteriorate. The exact cause of this deterioration is not known. Many researchers believe that several factors combined are involved: free radicals, accelerated aging, environmental toxins, and genetic predisposition. Exposure to an environmental toxin , such as a pesticide, that inhibits dopamine production and produces free radicals and oxidation damage may be involved.
Symtoms of Parkinson's Disease
Treatment of Parkinson's Disease
There is no cure for Parkinson's Disease disease. Medication can provide relief to its patient. Medication selection and dosage is tailored to the individual. The physician considers factors such as severity of symptoms, age, and presence of other medical conditions. Levodopa and carbidopa combined (Sinemet®) is the used in Parkinson's therapy drugs like Anticholinergics, Amantadine, Selegiline (Deprenyl), Dopamine, agonists, Apomorphine.
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